The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury

The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury

Paralysis following spinal cord injury (SCI) is due to interruption of axons and their failure to regenerate. It has been suggested that the small GTPase RhoA may be an intracellular signaling convergence point for several types of growth-inhibiting extracellular molecules. Even if this is true in v...

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Bibliographic Details
Main Authors: Jianli Hu, Guixin Zhang, William Rodemer, Li-Qing Jin, Michael Shifman, Michael E. Selzer
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Neurobiology of Disease
Subjects:
RhoA
Axon regeneration
Neuronal death
FLICA
Spinal cord injury
Lamprey
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116302649

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http://www.sciencedirect.com/science/article/pii/S0969996116302649

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