Design and Production of Bispecific Antibodies

Design and Production of Bispecific Antibodies

With the current biotherapeutic market dominated by antibody molecules, bispecific antibodies represent a key component of the next-generation of antibody therapy. Bispecific antibodies can target two different antigens at the same time, such as simultaneously binding tumor cell receptors and recrui...

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Bibliographic Details
Main Authors: Qiong Wang, Yiqun Chen, Jaeyoung Park, Xiao Liu, Yifeng Hu, Tiexin Wang, Kevin McFarland, Michael J. Betenbaugh
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Antibodies
Subjects:
single-chain variable fragment (scFv)
bispecific antibody
quadroma technology
knobs-into-holes
CrossMAb
bispecific T-cell engager (BiTE)
Online Access:https://www.mdpi.com/2073-4468/8/3/43

Internet

https://www.mdpi.com/2073-4468/8/3/43

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