HNF1α defect influences post-prandial lipid regulation.

Hepatocyte nuclear factor 1 alpha (HNF1α) defects cause Mature Onset Diabetes of the Young type 3 (MODY3), characterized by defects in beta-cell insulin secretion. However, HNF1α is involved in many other metabolic pathways with relevance for monogenic or polygenic type 2 diabetes. We aimed to inves...

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Bibliographic Details
Main Authors: Matthieu St-Jean, François Boudreau, André C Carpentier, Marie-France Hivert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5426708?pdf=render