Comparative analysis reveals conservation in genome organization among intestinal Cryptosporidium species and sequence divergence in potential secreted pathogenesis determinants among major human-infecting species

Comparative analysis reveals conservation in genome organization among intestinal Cryptosporidium species and sequence divergence in potential secreted pathogenesis determinants among major human-infecting species

Abstract Background Cryptosporidiosis is a major cause of gastrointestinal diseases in humans and other vertebrates. Previous analyses of invasion-related proteins revealed that Cryptosporidium parvum, Cryptosporidium hominis, and Cryptosporidium ubiquitum mainly differed in copy numbers of secreted...

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Bibliographic Details
Main Authors: Zhixiao Xu, Yaqiong Guo, Dawn M. Roellig, Yaoyu Feng, Lihua Xiao
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Genomics
Subjects:
Cryptosporidium chipmunk genotype I
Comparative genomics
MEDLE family proteins
Insulinase-like proteases
ABC transporters
Online Access:http://link.springer.com/article/10.1186/s12864-019-5788-9

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http://link.springer.com/article/10.1186/s12864-019-5788-9

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