Antitumor Activity of Asperphenin A, a Lipopeptidyl Benzophenone from Marine-Derived <i>Aspergillus</i> sp. Fungus, by Inhibiting Tubulin Polymerization in Colon Cancer Cells

Antitumor Activity of Asperphenin A, a Lipopeptidyl Benzophenone from Marine-Derived <i>Aspergillus</i> sp. Fungus, by Inhibiting Tubulin Polymerization in Colon Cancer Cells

Marine-derived microorganisms are a valuable source of novel bioactive natural products. Asperphenin A is a lipopeptidyl benzophenone metabolite isolated from large-scale cultivation of marine-derived <i>Aspergillus</i> sp. fungus. The compound has shown potent antiproliferative activity...

Full description

Bibliographic Details
Main Authors: Song Yi Bae, Lijuan Liao, So Hyun Park, Won Kyung Kim, Jongheon Shin, Sang Kook Lee
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Marine Drugs
Subjects:
marine microorganism metabolite
<i>aspergillus</i> sp. fungus
asperphenins
colon cancer
antimitotic agent
tubulin polymerization
Online Access:https://www.mdpi.com/1660-3397/18/2/110

Internet

https://www.mdpi.com/1660-3397/18/2/110

Similar Items