CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β.
Cell-surface transferrin receptor (CD71+) erythroid cells are abundant in newborns with immunomodulatory properties. Here, we show that neonatal CD71+ erythroid cells express significant levels of V-domain Immunoglobulin (Ig) Suppressor of T Cell Activation (VISTA) and, via constitutive production o...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-12-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.2006649 |