CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β.

Cell-surface transferrin receptor (CD71+) erythroid cells are abundant in newborns with immunomodulatory properties. Here, we show that neonatal CD71+ erythroid cells express significant levels of V-domain Immunoglobulin (Ig) Suppressor of T Cell Activation (VISTA) and, via constitutive production o...

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Bibliographic Details
Main Authors: Shima Shahbaz, Najmeh Bozorgmehr, Petya Koleva, Afshin Namdar, Juan Jovel, Roy A Fava, Shokrollah Elahi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006649