PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses
Abstract Mitochondria regulate not only cell functions through energy generation but also aging-associated cell phenotypes. Impaired mitochondrial structural and functional integrity accompanied by excessive mitochondrial reactive oxygen species (mtROS) production is associated with enhanced program...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-10-01
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| Series: | Inflammation and Regeneration |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41232-018-0077-6 |