PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses
Abstract Mitochondria regulate not only cell functions through energy generation but also aging-associated cell phenotypes. Impaired mitochondrial structural and functional integrity accompanied by excessive mitochondrial reactive oxygen species (mtROS) production is associated with enhanced program...
Main Authors: | Kazuya Tsubouchi, Jun Araya, Kazuyoshi Kuwano |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | Inflammation and Regeneration |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s41232-018-0077-6 |
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