Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma

Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma

The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.

Bibliographic Details
Main Authors: Weiwei Tao, Chengwei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu, Haidong Huang, Qiulian Wu, Andrew E. Sloan, Jennifer S. Yu, Xiaoxia Li, George R. Stark, Jeremy N. Rich, Shideng Bao
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16827-z

Internet

https://doi.org/10.1038/s41467-020-16827-z

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