Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

Background: Plasmodium falciparum causes placental malaria, which results in adverse outcomes for mother and child. P. falciparum-infected erythrocytes that express the parasite protein VAR2CSA on their surface can bind to placental chondroitin sulfate A. It has been hypothesized that naturally acqu...

Full description

Bibliographic Details
Main Authors: Elizabeth H Aitken, Timon Damelang, Amaya Ortega-Pajares, Agersew Alemu, Wina Hasang, Saber Dini, Holger W Unger, Maria Ome-Kaius, Morten A Nielsen, Ali Salanti, Joe Smith, Stephen Kent, P Mark Hogarth, Bruce D Wines, Julie A Simpson, Amy W Chung, Stephen J Rogerson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
immunity
pregnancy
Plasmodium falciparum
VAR2CSA
functional antibody
placenta
Online Access:https://elifesciences.org/articles/65776

Internet

https://elifesciences.org/articles/65776

Similar Items