Increase in tumor control and normal tissue complication probabilities in advanced head-and-neck cancer for dose-escalated intensity-modulated photon and proton therapy

Increase in tumor control and normal tissue complication probabilities in advanced head-and-neck cancer for dose-escalated intensity-modulated photon and proton therapy

Introduction:Presently used radio-chemotherapy regimens result in moderate local control rates for patients with advanced head and neck squamous cell carcinoma (HNSCC). Dose escalation (DE) may be an option to improve patient outcome, but may also increase the risk of toxicities in healthy tissue. T...

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Bibliographic Details
Main Authors: Annika eJakobi, Armin eLühr, Kristin eStützer, Anna eBandurska-Luque, Steffen eLöck, Mechthild eKrause, Michael eBaumann, Rosalind ePerrin, Christian eRichter
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Oncology
Subjects:
Proton radiotherapy
head-and-neck cancer
Dose-escalation
tumor control probability
Normal tissue complication probability
Photon radiotherapy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00256/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00256/full

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