Identification of mutation in 3'-end of exon 15 of APC gene in familial adenomatous polyposis patients

Identification of mutation in 3'-end of exon 15 of APC gene in familial adenomatous polyposis patients

Background: Familial adenomatous polyposis (FAP) is a hereditary precancerous syndrome and is characterized by the manifestation of adenomatous polyps in the colon and rectum at an early age. Germline mutations of APC gene cause FAP. This study aimed to investigate about the part of 3'-end of e...

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Bibliographic Details
Main Authors: Habibollahi H, Ranji N, Khazaei-Koohpar Z, Kamalifar HS
Format: Article
Language:fas
Published: Kashan University of Medical Sciences and Health Services 2020-02-01
Series:Fiyz̤
Subjects:
apc gene
colorectal cancer
familial adenomatous polyposis
germinal mutation
missense mutation
Online Access:http://feyz.kaums.ac.ir/article-1-3778-en.html

Internet

http://feyz.kaums.ac.ir/article-1-3778-en.html

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