Complexation with Random Methyl-β-Cyclodextrin and (2-Hydroxypropyl)-β-Cyclodextrin Promotes Chrysin Effect and Potential for Liver Fibrosis Therapy

Complexation with Random Methyl-β-Cyclodextrin and (2-Hydroxypropyl)-β-Cyclodextrin Promotes Chrysin Effect and Potential for Liver Fibrosis Therapy

Liver fibrosis results from chronic liver injury and is characterized by the accumulation of extracellular matrix in excess driven by hepatic stellate cells (HSCs) activation. Chrysin (CHR) is a natural flavonoid that is limited by its low solubility to exert its anti-inflammatory, antioxidant and a...

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Bibliographic Details
Main Authors: Simona-Rebeca Ignat, Sorina Dinescu, Judit Váradi, Ferenc Fenyvesi, Thi Le Phuong Nguyen, Alina Ciceu, Anca Hermenean, Marieta Costache
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Materials
Subjects:
chrysin
cyclodextrins
liver fibrosis
hepatic stellate cells
biocompatibility
anti-inflammatory
Online Access:https://www.mdpi.com/1996-1944/13/21/5003

Internet

https://www.mdpi.com/1996-1944/13/21/5003

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