DNA damage induced during mitosis undergoes DNA repair synthesis.

DNA damage induced during mitosis undergoes DNA repair synthesis.

Understanding the mitotic DNA damage response (DDR) is critical to our comprehension of cancer, premature aging and developmental disorders which are marked by DNA repair deficiencies. In this study we use a micro-focused laser to induce DNA damage in selected mitotic chromosomes to study the subseq...

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Bibliographic Details
Main Authors: Veronica Gomez Godinez, Sami Kabbara, Adria Sherman, Tao Wu, Shirli Cohen, Xiangduo Kong, Jose Luis Maravillas-Montero, Zhixia Shi, Daryl Preece, Kyoko Yokomori, Michael W Berns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227849

Internet

https://doi.org/10.1371/journal.pone.0227849

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