Proteome sampling by the HLA class I antigen processing pathway.

The peptide repertoire that is presented by the set of HLA class I molecules of an individual is formed by the different players of the antigen processing pathway and the stringent binding environment of the HLA class I molecules. Peptide elution studies have shown that only a subset of the human pr...

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Bibliographic Details
Main Authors: Ilka Hoof, Debbie van Baarle, William H Hildebrand, Can Keşmir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3355062?pdf=render