Reverse Regulatory Pathway (H2S / PGE2 / MMP) in Human Aortic Aneurysm and Saphenous Vein Varicosity.

Hydrogen sulfide (H2S) is a mediator with demonstrated protective effects for the cardiovascular system. On the other hand, prostaglandin (PG)E2 is involved in vascular wall remodeling by regulating matrix metalloproteinase (MMP) activities. We tested the hypothesis that endogenous H2S may modulate...

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Main Authors: Ingrid Gomez, Gulsev Ozen, Catherine Deschildre, Yasmine Amgoud, Lilia Boubaya, Isabelle Gorenne, Chabha Benyahia, Thomas Roger, Guy Lesèche, Erwan Galardon, Gokce Topal, Marie-Paule Jacob, Dan Longrois, Xavier Norel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4928935?pdf=render