The Receptors that Mediate the Direct Lethality of Anthrax Toxin

Tumor endothelium marker-8 (TEM8) and capillary morphogenesis protein-2 (CMG2) are the two well-characterized anthrax toxin receptors, each containing a von Willebrand factor A (vWA) domain responsible for anthrax protective antigen (PA) binding. Recently, a cell-based analysis was used to implicate...

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Bibliographic Details
Main Authors: Stephen H. Leppla, Benjamin Hoover, Yi Zhang, Shihui Liu
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/5/1/1