AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts
Transplant vasculopathy (TV), characterized by obstructive lesions in affected vessels, represents one of the long-term complications of cardiac transplantation. Activation of the transcription factor activator protein-1 (AP-1) is implicated in smooth muscle cell (SMC) phenotypic switch from contrac...
Main Authors: | Anca Remes, Maximilian Franz, Franziska Mohr, Antje Weber, Kleopatra Rapti, Andreas Jungmann, Matthias Karck, Markus Hecker, Klaus Kallenbach, Oliver J. Müller, Rawa Arif, Andreas H. Wagner |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
|
Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S232905011930107X |
Similar Items
-
Cardiac Allograft Vasculopathy in Human and Mouse /
by: Armstrong, Arthur T.
Published: (1996) -
AAV recombineering with single strand oligonucleotides.
by: Matthew L Hirsch, et al.
Published: (2009-11-01) -
Cardiac allograft vasculopathy: How can it be predicted?
by: Rita Calé, et al.
Published: (2020-04-01) -
Cardiac allograft vasculopathy: How can it be predicted?
by: Rita Calé, et al.
Published: (2020-04-01) -
Diagnosis, prevention and treatment of cardiac allograft vasculopathy
by: Rita Calé, et al.
Published: (2012-11-01)