Increased Indoleamine 2,3-Dioxygenase Levels at the Onset of Sjögren’s Syndrome in SATB1-Conditional Knockout Mice

Increased Indoleamine 2,3-Dioxygenase Levels at the Onset of Sjögren’s Syndrome in SATB1-Conditional Knockout Mice

Sjögren’s syndrome (SS) is a chronic autoimmune disease characterized by dysfunction of salivary and lacrimal glands, resulting in xerostomia (dry mouth) and keratoconjunctivitis sicca (dry eyes). Autoantibodies, such as anti-SSA and anti-SSB antibodies, are hallmarks and important diagnostic factor...

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Bibliographic Details
Main Authors: Yuriko Tanaka, Mayu Onozato, Tetuo Mikami, Terumi Kohwi-Shigematsu, Takeshi Fukushima, Motonari Kondo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
autoimmunity
Sjögren’s syndrome
interferon γ
tryptophan metabolism
Online Access:https://www.mdpi.com/1422-0067/22/18/10125

Internet

https://www.mdpi.com/1422-0067/22/18/10125

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