A Novel Glutathione <i>S</i>-Transferase Gtt2 Class (VpGSTT2) Is Found in the Genome of the AHPND/EMS <i>Vibrio parahaemolyticus</i> Shrimp Pathogen

A Novel Glutathione <i>S</i>-Transferase Gtt2 Class (VpGSTT2) Is Found in the Genome of the AHPND/EMS <i>Vibrio parahaemolyticus</i> Shrimp Pathogen

Glutathione S-transferases are a family of detoxifying enzymes that catalyze the conjugation of reduced glutathione (GSH) with different xenobiotic compounds using either Ser, Tyr, or Cys as a primary catalytic residue. We identified a novel GST in the genome of the shrimp pathogen <i>V. parah...

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Bibliographic Details
Main Authors: Ignacio Valenzuela-Chavira, David O. Corona-Martinez, Karina D. Garcia-Orozco, Melissa Beltran-Torres, Filiberto Sanchez-Lopez, Aldo A. Arvizu-Flores, Rocio Sugich-Miranda, Alonso A. Lopez-Zavala, Ramon E. Robles-Zepeda, Maria A. Islas-Osuna, Adrian Ochoa-Leyva, Michael D. Toney, Hugo Serrano-Posada, Rogerio R. Sotelo-Mundo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxins
Subjects:
glutathione s-transferase (GST)
<i>Vibrio parahaemolyticus</i>
Gtt2 class
glutathione (GSH)
kinetic isotope effect
crystal structure
Online Access:https://www.mdpi.com/2072-6651/13/9/664

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https://www.mdpi.com/2072-6651/13/9/664

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