Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load.

Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load.

HIV virulence, i.e. the time of progression to AIDS, varies greatly among patients. As for other rapidly evolving pathogens of humans, it is difficult to know if this variance is controlled by the genotype of the host or that of the virus because the transmission chain is usually unknown. We apply t...

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Main Authors: Samuel Alizon, Viktor von Wyl, Tanja Stadler, Roger D Kouyos, Sabine Yerly, Bernard Hirschel, Jürg Böni, Cyril Shah, Thomas Klimkait, Hansjakob Furrer, Andri Rauch, Pietro L Vernazza, Enos Bernasconi, Manuel Battegay, Philippe Bürgisser, Amalio Telenti, Huldrych F Günthard, Sebastian Bonhoeffer, Swiss HIV Cohort Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20941398/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20941398/pdf/?tool=EBI

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