Hemagglutinin-targeting Artificial MicroRNAs Expressed by Adenovirus Protect Mice From Different Clades of H5N1 Infection

Hemagglutinin-targeting Artificial MicroRNAs Expressed by Adenovirus Protect Mice From Different Clades of H5N1 Infection

Influenza virus (IV) is a continuously evolving virus that widely spreads in humans and contributes to substantial morbidity and mortality. Re-emergence of human infection with avian influenza virus H5N1 poses extra challenge to IV control. Artificial microRNA (amiRNA)-mediated RNA interference has...

Full description

Bibliographic Details
Main Authors: Xinying Tang, Hongbo Zhang, Yufeng Song, Dongming Zhou, Jieru Wang
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
adenovirus
artificial microRNA
H5N1
influenza virus
RNAi
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117300392

Internet

http://www.sciencedirect.com/science/article/pii/S2162253117300392

Similar Items