Ethanol causes protein precipitation--new safety issues for catheter locking techniques.

OBJECTIVE: The ethanol lock technique has shown great potential to eradicate organisms in biofilms and to treat or prevent central venous catheter related infections. Following instillation of ethanol lock solution, however, the inherent density gradient between blood and ethanol causes gravity indu...

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Bibliographic Details
Main Authors: Gernot Schilcher, Axel Schlagenhauf, Daniel Schneditz, Hubert Scharnagl, Werner Ribitsch, Robert Krause, Alexander R Rosenkranz, Tatjana Stojakovic, Joerg H Horina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877335?pdf=render