Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations.
The accumulation of somatic mitochondrial DNA (mtDNA) mutations is implicated in aging and common diseases of the elderly, including cancer and neurodegenerative disease. However, the mechanisms that influence the frequency of somatic mtDNA mutations are poorly understood. To develop a simple invert...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3916223?pdf=render |