Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility.

Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility.

Histamine H(3) receptor (Hrh3/H(3)R) is primarily expressed by neurons in the central nervous system (CNS) where it functions as a presynaptic inhibitory autoreceptor and heteroreceptor. Previously, we identified an H(3)R-mediated central component in susceptibility to experimental allergic encephal...

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Main Authors: Dimitry N Krementsov, Emma H Wall, Rebecca A Martin, Meenakumari Subramanian, Rajkumar Noubade, Roxana Del Rio, Gary M Mawe, Jeffrey P Bond, Matthew E Poynter, Elizabeth P Blankenhorn, Cory Teuscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3718788?pdf=render

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http://europepmc.org/articles/PMC3718788?pdf=render

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