Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides

Several cells of myeloid origin, such as monocytes and macrophages are involved in various human disorders, including cancer and inflammatory diseases. Hence, they represent attractive therapeutic targets. Here we developed three lytic hybrid peptides, by fusing a monocyte- and macrophage-binding pe...

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Bibliographic Details
Main Authors: Mouldy Sioud, Solveig Pettersen, Ieva Ailte, Yngvar Fløisand
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1088