Deciphering Epithelial–Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

Deciphering Epithelial–Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

Epithelial–mesenchymal transition (EMT), the process by which epithelial cells can convert into motile mesenchymal cells, plays an important role in development and wound healing but is also involved in cancer progression. It is increasingly recognized that EMT is a dynamic process involving multipl...

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Bibliographic Details
Main Authors: Gerhard A. Burger, Erik H. J. Danen, Joost B. Beltman
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Oncology
Subjects:
epithelial–mesenchymal transition
computational modeling
cancer progression
cell migration
stemness
cell metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00162/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00162/full

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