Critical roles of super-enhancers in the pathogenesis of autoimmune diseases

Abstract The super-enhancer (SE) is a cluster of enhancers involved in cell differentiation via enhanced gene expression that determines cell identity. Meanwhile, genome-wide association studies (GWASs) have reported the presence of gene clusters containing single nucleotide polymorphisms (SNPs) sus...

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Bibliographic Details
Main Authors: Kaoru Yamagata, Shingo Nakayamada, Yoshiya Tanaka
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Inflammation and Regeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41232-020-00124-9