IOX-101, a novel small molecule, reduces AML cell proliferation by Akt enzyme inhibition

Cancer of the blood continues to be a major mortality factor globally. Arylidene compounds are well known for their anticancer effects. Here we describe the biological efficacy of IOX-101, a potential lead-compound of arylidene in acute myeloid leukemia (AML). Initially, molecular docking analysis w...

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Bibliographic Details
Main Authors: Prasanna Rajagopalan, Raju Martin, Aseeri Hateem, Helal Ismail M., Elbessoumy Ashraf A.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2018-01-01
Series:Archives of Biological Sciences
Subjects:
Akt
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2018/0354-46641700049R.pdf