C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation processes. Here we show that during pre-B-cell-to-macrophage transdifferentiation,...

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Bibliographic Details
Main Authors: Chris van Oevelen, Samuel Collombet, Guillermo Vicent, Maarten Hoogenkamp, Cyrille Lepoivre, Aimee Badeaux, Lars Bussmann, Jose Luis Sardina, Denis Thieffry, Miguel Beato, Yang Shi, Constanze Bonifer, Thomas Graf
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001885