C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis
Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation processes. Here we show that during pre-B-cell-to-macrophage transdifferentiation,...
Main Authors: | Chris van Oevelen, Samuel Collombet, Guillermo Vicent, Maarten Hoogenkamp, Cyrille Lepoivre, Aimee Badeaux, Lars Bussmann, Jose Luis Sardina, Denis Thieffry, Miguel Beato, Yang Shi, Constanze Bonifer, Thomas Graf |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-08-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671115001885 |
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