Dimethyl Sulfoxide-Free Cryopreservation of Human Umbilical Cord Mesenchymal Stem Cells Based on Zwitterionic Betaine and Electroporation

Dimethyl Sulfoxide-Free Cryopreservation of Human Umbilical Cord Mesenchymal Stem Cells Based on Zwitterionic Betaine and Electroporation

The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily permeable and able to protect MSCs from cryo-injuries,...

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Bibliographic Details
Main Authors: Lei Gao, Qianqian Zhou, Yulong Zhang, Sujing Sun, Liping Lv, Ping Ma, Jing Yang, Min Liu, Lei Zhang, Xiaohui Wang, Linsheng Zhan
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
betaine
bioluminescence imaging
cryoprotectant
molecule delivery
reactive oxygen species
Online Access:https://www.mdpi.com/1422-0067/22/14/7445

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https://www.mdpi.com/1422-0067/22/14/7445

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