Local and systemic RAGE axis changes in pulmonary hypertension: CTEPH and iPAH.

Local and systemic RAGE axis changes in pulmonary hypertension: CTEPH and iPAH.

OBJECTIVE:The molecular determinants of chronic thromboembolic pulmonary hypertension (CTEPH) and idiopathic pulmonary arterial hypertension (iPAH) remain poorly understood. The receptor for advanced glycation endproducts (RAGE) and its ligands: HMGB1 and S100A9 are involved in inflammatory disorder...

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Bibliographic Details
Main Authors: Bernhard Moser, Anna Megerle, Christine Bekos, Stefan Janik, Tamás Szerafin, Peter Birner, Ana-Iris Schiefer, Michael Mildner, Irene Lang, Nika Skoro-Sajer, Roela Sadushi-Kolici, Shahrokh Taghavi, Walter Klepetko, Hendrik Jan Ankersmit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4154707?pdf=render

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http://europepmc.org/articles/PMC4154707?pdf=render

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