Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure

Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure

Abstract Background Linoleic acid is the major fatty acid moiety of cardiolipin, which is central to the assembly of components involved in mitochondrial oxidative phosphorylation (OXPHOS). Although linoleic acid is an essential nutrient, its excess intake is harmful to health. On the other hand, li...

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Bibliographic Details
Main Authors: Satoshi Maekawa, Shingo Takada, Hideo Nambu, Takaaki Furihata, Naoya Kakutani, Daiki Setoyama, Yasushi Ueyanagi, Dongchon Kang, Hisataka Sabe, Shintaro Kinugawa
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Cell Communication and Signaling
Subjects:
Supercomplex
Myocardial infarction
Cardiolipin
Succinate dehydrogenase
Respirasome
Online Access:http://link.springer.com/article/10.1186/s12964-019-0445-0

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http://link.springer.com/article/10.1186/s12964-019-0445-0

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