Adipose-Derived Mesenchymal Stem Cells Ameliorating Pseudomonas aeruginosa–induced Acute Lung Infection via Inhibition of NLRC4 Inflammasome

Adipose-Derived Mesenchymal Stem Cells Ameliorating Pseudomonas aeruginosa–induced Acute Lung Infection via Inhibition of NLRC4 Inflammasome

BackgroundPseudomonas aeruginosa (PA) is one of the most common Gram-negative bacteria causing hospital-acquired pulmonary infection, with high drug resistance and mortality. Therefore, it is urgent to introduce new non-antibiotic treatment strategies. Mesenchymal stem cells (MSCs), as important mem...

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Bibliographic Details
Main Authors: Lu-lu Li, Ying-gang Zhu, Xin-ming Jia, Dong Liu, Jie-ming Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
inflammasome
NLRC4
mesenchymal stem cells
Pseudomonas aeruginosa
acute pulmonary infection
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.581535/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.581535/full

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