GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis

Mucormycosis caused by Rhizopus species is a fungal infection with often fatal prognosis. Inhalation of spores is the major route of entry, with nasal and alveolar epithelial cells among the first cells that encounter the fungi. In patients with hematologic malignancies or those undergoing cytotoxic...

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Bibliographic Details
Main Authors: Abdullah Alqarihi, Teclegiorgis Gebremariam, Yiyou Gu, Marc Swidergall, Sondus Alkhazraji, Sameh S. M. Soliman, Vincent M. Bruno, John E. Edwards, Scott G. Filler, Priya Uppuluri, Ashraf S. Ibrahim
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
grp78
integrin β1
rhizopus
mucormycosis
cell invasion
epithelial cells
mice
Online Access:https://doi.org/10.1128/mBio.01087-20

Internet

https://doi.org/10.1128/mBio.01087-20

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