MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1

MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1

Interleukin-13 (IL-13) is an important Type 2 T helper (Th2) cytokine, controlling biological functions in epithelium and has been linked to asthma, atopic dermatitis and ulcerative colitis (UC). Interleukin-13 signals through IL-13 receptor α-1 (IL13RA1 (gene) and IL13Rα1 (protein)), a receptor tha...

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Bibliographic Details
Main Authors: Markus Gwiggner, Rocio T. Martinez-Nunez, Simon R. Whiteoak, Victor P. Bondanese, Andy Claridge, Jane E. Collins, J. R. Fraser Cummings, Tilman Sanchez-Elsner
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Genes
Subjects:
ulcerative colitis
microRNAs
interleukin-13
inflammation
epithelium
gut
Online Access:http://www.mdpi.com/2073-4425/9/2/85

Internet

http://www.mdpi.com/2073-4425/9/2/85

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