Loss of PR55α promotes proliferation and metastasis by activating MAPK/AKT signaling in hepatocellular carcinoma

Abstract Background PR55α plays important roles in oncogenesis and progression of numerous malignancies. However, its role in hepatocellular carcinoma (HCC) is unclear. This study aims to characterize the functions of PR55α in HCC. Methods PR55α expressions in HCC tissues and paired healthy liver sa...

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Bibliographic Details
Main Authors: JiangSheng Zhao, GuoFeng Chen, Jingqi Li, Shiqi Liu, Quan Jin, ZhengWei Zhang, Fuzhen Qi, JianHuai Zhang, JianBo Xu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-01796-0