Development and validation of an HPLC method for the determination of fluorouracil in polymeric nanoparticles

The objective of this work was to develop and validate a rapid high performance liquid chromatography (HPLC) method for the quantitative analysis of fluorouracil (5-FU) in polymeric nanoparticles. Chromatographic analyses were performed on an RP C18 column with a mobile phase consisting of acetonitr...

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Bibliographic Details
Main Authors: Ana Cristina de Mattos, Najeh Maissar Khalil, Rubiana Mara Mainardes
Format: Article
Language:English
Published: Universidade de São Paulo 2013-03-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000100013