Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury

Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury

Abstract Background Aucubin (Au), an iridoid glycoside from natural plants, has antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain injury (TBI) model remain unknown. We explored the potential role of Au in an H2O2-induced oxidant damage in primary cortical n...

Full description

Bibliographic Details
Main Authors: Han Wang, Xiao-Ming Zhou, Ling-Yun Wu, Guang-Jie Liu, Wei-Dong Xu, Xiang-Sheng Zhang, Yong-Yue Gao, Tao Tao, Yan Zhou, Yue Lu, Juan Wang, Chu-Lei Deng, Zong Zhuang, Chun-Hua Hang, Wei Li
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Neuroinflammation
Subjects:
Traumatic brain injury (TBI)
Aubucin
Oxidative stress
Inflammation
Nuclear factor erythroid-2 related factor 2 (Nrf2)
Online Access:http://link.springer.com/article/10.1186/s12974-020-01863-9

Internet

http://link.springer.com/article/10.1186/s12974-020-01863-9

Similar Items