PKG1α oxidation negatively regulates food seeking behaviour and reward

Genes that are highly conserved in food seeking behaviour, such as protein kinase G (PKG), are of interest because of their potential role in the global obesity epidemic. PKG1α can be activated by binding of cyclic guanosine monophosphate (cGMP) or oxidant-induced interprotein disulfide bond formati...

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Bibliographic Details
Main Authors: Celine Duraffourd, Robert T.R. Huckstepp, Ingke Braren, Cathy Fernandes, Olivier Brock, Alessio Delogu, Oleksandra Prysyazhna, Joseph Burgoyne, Philip Eaton
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718309716