Human Albumin Fragments Nanoparticles as PTX Carrier for Improved Anti-cancer Efficacy

Human Albumin Fragments Nanoparticles as PTX Carrier for Improved Anti-cancer Efficacy

For enhanced anti-cancer performance, human serum albumin fragments (HSAFs) nanoparticles (NPs) were developed as paclitaxel (PTX) carrier in this paper. Human albumins were broken into fragments via degradation and crosslinked by genipin to form HSAF NPs for better biocompatibility, improved PTX dr...

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Bibliographic Details
Main Authors: Liang Ge, Xinru You, Jun Huang, Yuejian Chen, Li Chen, Ying Zhu, Yuan Zhang, Xiqiang Liu, Jun Wu, Qian Hai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
human serum albumin fragments
nanoparticle
paclitaxel
drug delivery
anticancer
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00582/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00582/full

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