Genetic and clinical predictors of CD4 lymphocyte recovery during suppressive antiretroviral therapy: Whole exome sequencing and antiretroviral therapy response phenotypes.

Genetic and clinical predictors of CD4 lymphocyte recovery during suppressive antiretroviral therapy: Whole exome sequencing and antiretroviral therapy response phenotypes.

Increase of peripheral blood CD4 lymphocyte counts is a key goal of combined antiretroviral therapy (cART); most, but not all, recipients respond adequately and promptly. A small number of studies have examined specific genetic factors associated with the extent of CD4 recovery. We report a genome-w...

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Bibliographic Details
Main Authors: Ruth Greenblatt, Peter Bacchetti, Ross Boylan, Kord Kober, Gayle Springer, Kathryn Anastos, Michael Busch, Mardge Cohen, Seble Kassaye, Deborah Gustafson, Bradley Aouizerat, Women’s Interagency HIV Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219201

Internet

https://doi.org/10.1371/journal.pone.0219201

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