Dynamic changes of behaviors, dentate gyrus neurogenesis and hippocampal miR-124 expression in rats with depression induced by chronic unpredictable mild stress

Dynamic changes of behaviors, dentate gyrus neurogenesis and hippocampal miR-124 expression in rats with depression induced by chronic unpredictable mild stress

The depression-like behavior phenotype, neurogenesis in the dentate gyrus and miR-124 expression in the hippocampus are the focus of current research on the pathogenesis of depression and antidepressant therapy. The present study aimed to clarify the dynamic changes of depression-like behavior, dent...

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Bibliographic Details
Main Authors: Yun-Ling Huang, Ning-Xi Zeng, Jie Chen, Jie Niu, Wu-Long Luo, Ping Liu, Can Yan, Li-Li Wu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
chronic unpredictable mild stress model; continuous observation; depression; depression-like behavior; dynamic changes; hippocampus; mir-124; neurogenesis dysfunction; neuronal loss
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1150;epage=1159;aulast=Huang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1150;epage=1159;aulast=Huang

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