Characterization of functional protein complexes from Alzheimer’s disease and healthy brain by mass spectrometry-based proteome analysis

Abstract Alzheimer’s disease (AD) is a complex neurodegenerative disorder with impaired protein activities. Proteins in the form of complexes have a ubiquitous role in diverse range of cellular functions. The key challenge is to identify novel disease associated protein complexes and their potential...

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Bibliographic Details
Main Authors: Beena Hasan, Ayesha Khan, Christof Lenz, Abdul R. Asif, Nikhat Ahmed
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93356-9