A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity

Human selenium-binding protein 1 (SELENBP1) was originally identified as a protein binding selenium, most likely as selenite. SELENBP1 is associated with cellular redox and thiol homeostasis in several respects, including its established role as a methanethiol oxidase that is involved in degradation...

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Main Authors: Karl Köhnlein, Nadine Urban, David Guerrero-Gómez, Holger Steinbrenner, Pavel Urbánek, Josephine Priebs, Philipp Koch, Christoph Kaether, Antonio Miranda-Vizuete, Lars-Oliver Klotz
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719308419