The Alzheimer’s Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides

by Gabriele Siegel, Hermeto Gerber, Philipp Koch, Oliver Bruestle, Patrick C. Fraering, Lawrence Rajendran
Published 2017-06-01

MicroRNA-based promotion of human neuronal differentiation and subtype specification.

by Laura Stappert, Lodovica Borghese, Beate Roese-Koerner, Sandra Weinhold, Philipp Koch, Stefanie Terstegge, Markus Uhrberg, Peter Wernet, Oliver Brüstle
Published 2013-01-01

Correction: MicroRNA-Based Promotion of Human Neuronal Differentiation and Subtype Specification.

by Laura Stappert, Lodovica Borghese, Beate Roese-Koerner, Sandra Weinhold, Philipp Koch, Stefanie Terstegge, Markus Uhrberg, Peter Wernet, Oliver Brüstle
Published 2013-01-01

Correction to: A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri

by Mario Baumgart, Emanuel Barth, Aurora Savino, Marco Groth, Philipp Koch, Andreas Petzold, Ivan Arisi, Matthias Platzer, Manja Marz, Alessandro Cellerino
Published 2019-11-01

A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri

by Mario Baumgart, Emanuel Barth, Aurora Savino, Marco Groth, Philipp Koch, Andreas Petzold, Ivan Arisi, Matthias Platzer, Manja Marz, Alessandro Cellerino
Published 2017-09-01

DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling

by Laura de Boni, Gilles Gasparoni, Carolin Haubenreich, Sascha Tierling, Ina Schmitt, Michael Peitz, Philipp Koch, Jörn Walter, Ullrich Wüllner, Oliver Brüstle
Published 2018-01-01

An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome

by Vira Iefremova, George Manikakis, Olivia Krefft, Ammar Jabali, Kevin Weynans, Ruven Wilkens, Fabio Marsoner, Björn Brändl, Franz-Josef Müller, Philipp Koch, Julia Ladewig
Published 2017-04-01

A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity

by Karl Köhnlein, Nadine Urban, David Guerrero-Gómez, Holger Steinbrenner, Pavel Urbánek, Josephine Priebs, Philipp Koch, Christoph Kaether, Antonio Miranda-Vizuete, Lars-Oliver Klotz
Published 2020-01-01

The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine

by Jerome Korzelius, Sina Azami, Tal Ronnen-Oron, Philipp Koch, Maik Baldauf, Elke Meier, Imilce A. Rodriguez-Fernandez, Marco Groth, Pedro Sousa-Victor, Heinrich Jasper
Published 2019-09-01

Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.

by Anna Falk, Philipp Koch, Jaideep Kesavan, Yasuhiro Takashima, Julia Ladewig, Michael Alexander, Ole Wiskow, Jignesh Tailor, Matthew Trotter, Steven Pollard, Austin Smith, Oliver Brüstle
Published 2012-01-01

Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein

by Saoussen Ben Halima, Sabyashachi Mishra, K. Muruga Poopathi Raja, Michael Willem, Antonio Baici, Kai Simons, Oliver Brüstle, Philipp Koch, Christian Haass, Amedeo Caflisch, Lawrence Rajendran
Published 2016-03-01

Functional neuronal cells generated by human parthenogenetic stem cells.

by Ruhel Ahmad, Wanja Wolber, Sigrid Eckardt, Philipp Koch, Jessica Schmitt, Ruslan Semechkin, Christian Geis, Manfred Heckmann, Oliver Brüstle, John K McLaughlin, Anna-Leena Sirén, Albrecht M Müller
Published 2012-01-01

HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

by Alicia Tapias, David Lázaro, Bo-Kun Yin, Seyed Mohammad Mahdi Rasa, Anna Krepelova, Erika Kelmer Sacramento, Paulius Grigaravicius, Philipp Koch, Joanna Kirkpatrick, Alessandro Ori, Francesco Neri, Zhao-Qi Wang
Published 2021-02-01

MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility

by Daniel Luxen, Gerrit H. Gielen, Anke Waha, Lukas Isselstein, Tim Müller, Philipp Koch, Jennifer Hammes, Albert Becker, Matthias Simon, Peter Wurst, Elmar Endl, Torsten Pietsch, Marco Gessi, Andreas Waha
Published 2017-02-01

Whole-brain 3D mapping of human neural transplant innervation

by Jonas Doerr, Martin Karl Schwarz, Dirk Wiedermann, Anke Leinhaas, Alina Jakobs, Florian Schloen, Inna Schwarz, Michael Diedenhofen, Nils Christian Braun, Philipp Koch, Daniel A. Peterson, Ulrich Kubitscheck, Mathias Hoehn, Oliver Brüstle
Published 2017-01-01

Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis

by Arne Sahm, Matthias Platzer, Philipp Koch, Yoshiyuki Henning, Martin Bens, Marco Groth, Hynek Burda, Sabine Begall, Saskia Ting, Moritz Goetz, Paul Van Daele, Magdalena Staniszewska, Jasmin Mona Klose, Pedro Fragoso Costa, Steve Hoffmann, Karol Szafranski, Philip Dammann
Published 2021-03-01

Alternative Animal Models of Aging Research

by Susanne Holtze, Ekaterina Gorshkova, Ekaterina Gorshkova, Stan Braude, Alessandro Cellerino, Alessandro Cellerino, Philip Dammann, Philip Dammann, Thomas B. Hildebrandt, Thomas B. Hildebrandt, Andreas Hoeflich, Steve Hoffmann, Philipp Koch, Eva Terzibasi Tozzini, Maxim Skulachev, Vladimir P. Skulachev, Arne Sahm
Published 2021-05-01