The Alzheimer’s Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides

by Gabriele Siegel, Hermeto Gerber, Philipp Koch, Oliver Bruestle, Patrick C. Fraering, Lawrence Rajendran
Published 2017-06-01

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer’s disease

by Hermeto Gerber, Sebastien Mosser, Benjamin Boury-Jamot, Michael Stumpe, Alessandra Piersigilli, Christine Goepfert, Joern Dengjel, Urs Albrecht, Fulvio Magara, Patrick C. Fraering
Published 2019-01-01

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

by Ajinkya Revandkar, Maria Luna Perciato, Alberto Toso, Abdullah Alajati, Jingjing Chen, Hermeto Gerber, Mitko Dimitrov, Andrea Rinaldi, Nicolas Delaleu, Emiliano Pasquini, Rocco D’Antuono, Sandra Pinton, Marco Losa, Letizia Gnetti, Alberto Arribas, Patrick Fraering, Francesco Bertoni, Alain Nepveu, Andrea Alimonti
Published 2016-12-01