Long Term Pharmacological Perturbation of Autophagy in Mice: Are HCQ Injections a Relevant Choice?

Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved catabolic process whose loss-of-function has been linked to a growing list of pathologies. Knockout mouse models of key autophagy genes have been instrumental in the demonstration of the critical functions of autophag...

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Bibliographic Details
Main Authors: Jean-Daniel Masson, Benoit Blanchet, Baptiste Periou, François-Jérôme Authier, Baharia Mograbi, Romain K Gherardi, Guillemette Crépeaux
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/3/47