Immunogenicity of chimeric MUC1-HER2 vaccine against breast cancer in mice

Objective(s): Breast cancer is one of the most common cancers in the world and is on the increase. MUC1 and HER2 as tumor-associated antigens (TAAs) are abnormally expressed to some extent in 75–80% of breast cancers.  In our present research, a novel chimeric MUC1-HER2 (HM) protein was designed and...

Full description

Bibliographic Details
Main Authors: Elaheh Gheybi, Ali Hatef Salmanian, Abbas Ali Imani Fooladi, Jafar Salimian, Hamideh Mahmoodzadeh Hosseini, Raheleh Halabian, Jafar Amani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_9919_84248188e236e6b6f85909cbd6bb44df.pdf